Familial atypical multiple mole melanoma syndrome

Also known as: B-K mole syndrome, FAMM-PC syndrome, FAMMM syndrome, Familial Clark nevus syndrome, Familial atypical mole syndrome, Familial atypical multiple mole melanoma-pancreatic carcinoma syndrome, Familial dysplastic nevus syndrome, Melanoma-pancreatic cancer syndrome

Definition

Orphanet

Familial atypical multiple mole melanoma (FAMMM) syndrome is an inherited genodermatosis characterized by the presence of multiple melanocytic nevi (often >50) and a family history of melanoma as well as, in a subset of patients, an increased risk of developing pancreatic cancer (see this term) and other malignancies.

Go To Source: Orphanet

Symptoms

Medical Term Other Names Description
Neoplasm of the pancreas Neoplasia of the pancreas, Pancreatic cancer, increased risk of pancreatic cancer, Cancer of the pancreas [more] A tumor (abnormal growth of tissue) of the pancreas.
Nevus Mole, Naevi, Naevus, Nevi [more] A nevus is a type of hamartoma that is a circumscribed stable malformation of the skin.
Melanoma Malignant melanoma, Skin cancer (melanoma) The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea).
Pancreatitis Pancreatic inflammation The presence of inflammation in the pancreas.
Melanocytic nevus Beauty mark, Melanocytic nevi, Nevocellular nevi, Melanocytic naevus, Noncancerous mole, Pigmented nevi, Pigmented naevi [more] A oval and round, colored (usually medium-to dark brown, reddish brown, or flesh colored) lesion. Typically, a melanocytic nevus is less than 6 mm in diameter, but may be much smaller or larger.

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